Jack A Elias Selected Research

Interleukin-10 (Interleukin 10)

1/2013	Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis.
11/2009	Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle.
9/2002	Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways.

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Jack A Elias Research Topics

Disease

74	Inflammation (Inflammations) 01/2023 - 03/2002
38	Fibrosis (Cirrhosis) 10/2022 - 03/2002
36	Asthma (Bronchial Asthma) 10/2022 - 07/2002
22	Pulmonary Fibrosis (Fibrosing Alveolitis) 05/2023 - 10/2002
17	Pneumonia (Pneumonitis) 01/2019 - 03/2002
12	Metaplasia 10/2022 - 03/2002
11	Infections 02/2022 - 06/2004
11	Hyperoxia 05/2012 - 08/2003
10	Neoplasms (Cancer) 12/2023 - 12/2008
10	Neoplasm Metastasis (Metastasis) 01/2022 - 05/2012
10	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 08/2006
10	Emphysema 06/2012 - 06/2005
9	Respiratory Hypersensitivity 08/2010 - 07/2002
8	Lung Injury 01/2016 - 04/2005
8	Acute Lung Injury 05/2012 - 10/2003
7	COVID-19 02/2022 - 09/2020
7	Lung Diseases (Lung Disease) 01/2022 - 07/2002
7	Airway Remodeling 03/2016 - 09/2002
6	Hyperplasia 01/2022 - 08/2003
6	Pulmonary Emphysema 01/2021 - 05/2005
5	Melanoma (Melanoma, Malignant) 01/2022 - 05/2012
5	Idiopathic Pulmonary Fibrosis 01/2022 - 06/2011
5	Vascular Remodeling 04/2013 - 10/2004
5	Edema (Dropsy) 11/2011 - 10/2004
4	Bronchopulmonary Dysplasia 05/2012 - 12/2004
4	Respiratory Insufficiency (Respiratory Failure) 02/2005 - 03/2002
3	Virus Diseases (Viral Diseases) 12/2015 - 08/2008
3	Eosinophilia 12/2005 - 08/2002
2	Neuroinflammatory Diseases 09/2023 - 01/2023
2	Macrophage Activation Syndrome 01/2021 - 11/2020
2	Insulin Resistance 01/2021 - 11/2009
2	Chronic Disease (Chronic Diseases) 11/2020 - 10/2019
2	Respiratory Syncytial Virus Infections 01/2019 - 11/2006
2	Hermanski-Pudlak Syndrome (Hermansky-Pudlak Syndrome) 01/2018 - 08/2015
2	Delayed Graft Function 01/2017 - 02/2013

Drug/Important Bio-Agent (IBA)

50	ChitinasesIBA 05/2023 - 06/2004
36	Interleukin-13IBA 10/2022 - 03/2002
35	Proteins (Proteins, Gene)FDA Link 09/2023 - 02/2004
29	CytokinesIBA 12/2023 - 08/2002
17	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2017 - 10/2004
15	Biomarkers (Surrogate Marker)IBA 09/2023 - 04/2008
13	AllergensIBA 11/2020 - 08/2002
10	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2022 - 04/2003
9	ChemokinesIBA 01/2023 - 03/2002
9	SmokeIBA 12/2015 - 12/2005
8	Peptide Hydrolases (Proteases)FDA Link 02/2022 - 01/2004
8	Bleomycin (Blenoxane)FDA LinkGeneric 01/2022 - 10/2002
8	ChitinIBA 01/2018 - 06/2004
8	Oxidants (Oxidizing Agents)IBA 01/2016 - 04/2005
7	InterleukinsIBA 01/2022 - 07/2002
6	Messenger RNA (mRNA)IBA 10/2019 - 09/2002
6	Interleukin-11 (Interleukin 11)IBA 12/2008 - 03/2003
5	Interleukin-6 (Interleukin 6)IBA 01/2022 - 10/2003
5	Oxygen (Dioxygen)IBA 01/2021 - 10/2003
5	Transforming Growth Factor beta1 (TGF beta 1)IBA 01/2015 - 12/2004
5	Interleukin-4 (Interleukin 4)IBA 01/2013 - 08/2002
4	Chitinase-3-Like Protein 1IBA 09/2023 - 01/2014
4	CollagenIBA 01/2022 - 03/2006
4	LigandsIBA 11/2021 - 02/2009
4	chitotriosidaseIBA 01/2021 - 05/2014
4	Small Interfering RNA (siRNA)IBA 01/2018 - 11/2006
4	Interleukin-17 (Interleukin 17)IBA 01/2013 - 04/2003
4	Transforming Growth Factor beta (TGF-beta)IBA 01/2011 - 01/2004
3	CateninsIBA 09/2023 - 08/2013
3	kasugamycinIBA 02/2022 - 01/2022
3	indium-bleomycinIBA 01/2022 - 03/2007
3	LipidsIBA 01/2021 - 05/2005
3	Immunoglobulin E (IgE)IBA 11/2020 - 12/2008
3	OvalbuminIBA 11/2020 - 08/2010
3	Antiviral Agents (Antivirals)IBA 09/2020 - 05/2011
3	Mitogen-Activated Protein KinasesIBA 01/2020 - 01/2006
3	Matrix Metalloproteinases (MMPs)IBA 01/2017 - 08/2002
3	AmphiregulinIBA 03/2016 - 12/2012
3	Interleukin-13 Receptors (Interleukin 13 Receptor)IBA 03/2016 - 01/2013
3	Interleukin-18 (Interleukin 18)IBA 12/2015 - 02/2007
3	EnzymesIBA 03/2015 - 08/2002
3	AntigensIBA 03/2015 - 10/2004
3	Semaphorins (Semaphorin)IBA 02/2015 - 05/2007
3	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 08/2013 - 05/2007
3	Interleukin-10 (Interleukin 10)IBA 01/2013 - 09/2002
3	Angiopoietin-2IBA 05/2012 - 05/2007
3	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 04/2012 - 04/2006
3	Poly I-CIBA 11/2011 - 08/2008
3	CaspasesIBA 05/2011 - 06/2005
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2011 - 10/2002
3	Adenosine (Adenocard)FDA LinkGeneric 05/2006 - 08/2003
3	Protease Inhibitors (Protease Inhibitor)IBA 01/2006 - 02/2004
2	Immune Checkpoint InhibitorsIBA 12/2023 - 01/2022
2	Anti-Asthmatic Agents (Antiasthmatic Drugs)IBA 10/2022 - 01/2022
2	AntibodiesIBA 01/2022 - 11/2021
2	C-Reactive ProteinIBA 01/2022 - 06/2014
2	RNA (Ribonucleic Acid)IBA 01/2022 - 03/2016
2	Bispecific AntibodiesIBA 01/2022 - 11/2021
2	HydrolasesIBA 01/2022 - 01/2022
2	Insulin (Novolin)FDA Link 01/2021 - 11/2009
2	Amyloid (Amyloid Fibrils)IBA 12/2020 - 01/2011
2	Peptides (Polypeptides)IBA 01/2018 - 03/2015
2	plexinIBA 12/2016 - 02/2015

Therapy/Procedure

8	Therapeutics 01/2022 - 10/2003
2	Transplantation 01/2022 - 02/2013